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ASB6

From Wikipedia, the free encyclopedia

ASB6
Identifiers
AliasesASB6, ankyrin repeat and SOCS box containing 6
External IDsOMIM: 615051; MGI: 1919573; HomoloGene: 9895; GeneCards: ASB6; OMA:ASB6 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_177999
NM_001202403
NM_017873

NM_133346

RefSeq (protein)

NP_001189332
NP_060343
NP_821066

NP_579924

Location (UCSC)Chr 9: 129.63 – 129.64 MbChr 2: 30.71 – 30.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ankyrin repeat and SOCS box protein 6 is a protein that in humans is encoded by the ASB6 gene.[5]

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000148331Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039483Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: ASB6 ankyrin repeat and SOCS box-containing 6".
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Further reading

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