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Abequosyltransferase

From Wikipedia, the free encyclopedia
abequosyltransferase
Identifiers
EC no.2.4.1.60
CAS no.37277-67-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, an abequosyltransferase (EC 2.4.1.60) is an enzyme that catalyzes the chemical reaction

CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid

Thus, the two substrates of this enzyme are CDP-abequose and D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid, whereas its two products are CDP and D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is CDP-abequose:D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid D-abequosyltransferase. This enzyme is also called trihexose diphospholipid abequosyltransferase.

References

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  • Osborn MJ, Weiner IM (1968). "Biosynthesis of a bacterial lipopolysaccharide. VI. Mechanism of incorporation of abequose into the O-antigen of Salmonella typhimurium". J. Biol. Chem. 243 (10): 2631–9. PMID 4297268.