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CEP55

From Wikipedia, the free encyclopedia
CEP55
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCEP55, C10orf3, CT111, URCC6, centrosomal protein 55, MARCH
External IDsOMIM: 610000; MGI: 1921357; HomoloGene: 10019; GeneCards: CEP55; OMA:CEP55 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001127182
NM_018131

NM_001164362
NM_028293
NM_028760
NM_001360663

RefSeq (protein)

NP_001120654
NP_060601

NP_001157834
NP_082569
NP_083036
NP_001347592

Location (UCSC)Chr 10: 93.5 – 93.53 MbChr 19: 38.04 – 38.06 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Centrosomal protein of 55 kDa (Cep55), is a protein that in humans is encoded by the CEP55 gene.[5][6]

Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division.[7] and cilia formation in neural stem cells.[8]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138180Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024989Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Fabbro M, Zhou BB, Takahashi M, Sarcevic B, Lal P, Graham ME, Gabrielli BG, Robinson PJ, Nigg EA, Ono Y, Khanna KK (Oct 2005). "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis". Dev Cell. 9 (4): 477–88. doi:10.1016/j.devcel.2005.09.003. PMID 16198290.
  6. ^ "Entrez Gene: CEP55 centrosomal protein 55kDa".
  7. ^ van der Horst A, Simmons J, Khanna KK (November 2009). "Cep55 stabilization is required for normal execution of cytokinesis". Cell Cycle. 8 (22): 3742–3749. doi:10.4161/cc.8.22.10047. PMID 19855176.
  8. ^ Behnam Rashidieh; Belal Shohayeb; Amanda Louise Bain; Patrick R. J. Fortuna; Debottam Sinha; Andrew Burgess; Richard Mills; Rachael C. Adams; J. Alejandro Lopez; Peter Blumbergs; John Finnie; Murugan Kalimutho; Michael Piper; James Edward Hudson; Dominic C. H. Ng; Kum Kum Khanna (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis". PLOS Genetics. 17 (10): e1009334. doi:10.1371/journal.pgen.1009334. PMC 8577787. PMID 34710087.
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Further reading

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