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Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase

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Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase
Identifiers
EC no.2.4.1.254
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
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MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

Cyanidin-3-O-glucoside 2-O-glucuronosyltransferase (EC 2.4.1.254, BpUGT94B1, UDP-glucuronic acid:anthocyanin glucuronosyltransferase, UDP-glucuronic acid:anthocyanidin 3-glucoside 2'-O-beta-glucuronosyltransferase, BpUGAT, UDP-D-glucuronate:cyanidin-3-O-beta-glucoside 2-O-beta-glucuronosyltransferase) is an enzyme with systematic name UDP-D-glucuronate:cyanidin-3-O-beta-D-glucoside 2-O-beta-D-glucuronosyltransferase.[1][2] This enzyme catalyses the following chemical reaction

UDP-D-glucuronate + cyanidin 3-O-beta-D-glucoside UDP + cyanidin 3-O-(2-O-beta-D-glucuronosyl)-beta-D-glucoside

The enzyme is highly specific for cyanidin 3-O-glucosides and UDP-D-glucuronate.

References

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  1. ^ Sawada S, Suzuki H, Ichimaida F, Yamaguchi MA, Iwashita T, Fukui Y, Hemmi H, Nishino T, Nakayama T (January 2005). "UDP-glucuronic acid:anthocyanin glucuronosyltransferase from red daisy (Bellis perennis) flowers. Enzymology and phylogenetics of a novel glucuronosyltransferase involved in flower pigment biosynthesis". The Journal of Biological Chemistry. 280 (2): 899–906. doi:10.1074/jbc.m410537200. PMID 15509561.
  2. ^ Osmani SA, Bak S, Imberty A, Olsen CE, Møller BL (November 2008). "Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses". Plant Physiology. 148 (3): 1295–308. doi:10.1104/pp.108.128256. PMC 2577238. PMID 18829982.
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