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DOB-2-DRAGONFLY-5-BUTTERFLY

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DOB-2-DRAGONFLY-5-BUTTERFLY
Identifiers
  • 1-(4-bromo-7,8-dihydro-6H-furo[2,3-g]chromen-9-yl)propan-2-amine
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC14H16BrNO2
Molar mass310.191 g·mol−1
3D model (JSmol)
  • CC(CC1=C2CCCOC2=C(C3=C1OC=C3)Br)N
  • InChI=1S/C14H16BrNO2/c1-8(16)7-11-9-3-2-5-17-14(9)12(15)10-4-6-18-13(10)11/h4,6,8H,2-3,5,7,16H2,1H3
  • Key:OEZJAFWOXYNISY-UHFFFAOYSA-N

DOB-2-DRAGONFLY-5-BUTTERFLY is a drug with an unusual furo[2,3-g]chromene core structure which acts as a 5-HT2A receptor agonist. It was first synthesised by David E. Nichols and colleagues in 2008, and while it is weaker than similar compounds such as Bromo-DragonFLY it is still the most potent among a number of related derivatives.[1][2]

See also

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References

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  1. ^ Schultz DM, Prescher JA, Kidd S, Marona-Lewicka D, Nichols DE, Monte A (June 2008). "'Hybrid' benzofuran-benzopyran congeners as rigid analogs of hallucinogenic phenethylamines". Bioorganic & Medicinal Chemistry. 16 (11): 6242–51. doi:10.1016/j.bmc.2008.04.030. PMC 2601679. PMID 18467103.
  2. ^ Trachsel D, Lehmann D, Enzensperger C (2013). Phenethylamine Von der Struktur zur Funktion. Nachtschatten Verlag AG. pp. 857–860. ISBN 978-3-03788-700-4.