Dioxifedrine
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Other names | Dioxifedrin; α-Methylepinephrine; α-Methyladrenaline; 3,4-Dihydroxyephedrine; Dioxyephedrine; Sor-N 49; Diphedran; LD-1205; 3,4,β-Trihydroxy-α,N-dimethylphenethylamine; 3,4,β-Trihydroxy-N-methylamphetamine |
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ECHA InfoCard | 100.030.639 |
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Formula | C10H15NO3 |
Molar mass | 197.234 g·mol−1 |
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Dioxifedrine (INN ), or dioxifedrin, also known as α-methylepinephrine or as 3,4-dihydroxyephedrine, is a sympathomimetic medication that was never marketed.[1][2][3][4] It is described as a β-adrenergic receptor agonist and bronchodilator.[1][5][6] The drug is a substituted phenethylamine and amphetamine and is the catecholamine (3,4-dihydroxylated) derivative of ephedrine and the amphetamine (α-methylated) analogue of epinephrine (adrenaline).[1][2] Analogues of dioxifedrine include dioxethedrin (α-methyl-N-ethylnorepinephrine), corbadrine (levonordefrin; α-methylnorepinephrine), and α-methyldopamine.[1]
References
[edit]- ^ a b c d Elks, J. (2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. p. 447. ISBN 978-1-4757-2085-3. Retrieved 2 September 2024.
- ^ a b "Dioxifedrine". PubChem. Retrieved 2 September 2024.
- ^ https://iris.who.int/bitstream/handle/10665/67830/WHO_EDM_QSM_2003.2.pdf
- ^ "CAS Common Chemistry". CAS Common Chemistry. 2 September 2024. Retrieved 2 September 2024.
- ^ "DIOXIFEDRINE". Inxight Drugs. Retrieved 2 September 2024.
- ^ https://ncithesaurus.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C65417