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OR5AS1

From Wikipedia, the free encyclopedia
OR5AS1
Identifiers
AliasesOR5AS1, OR11-168, olfactory receptor family 5 subfamily AS member 1
External IDsMGI: 3030945; HomoloGene: 74238; GeneCards: OR5AS1; OMA:OR5AS1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001001921

NM_146593

RefSeq (protein)

NP_001001921

NP_666804

Location (UCSC)Chr 11: 56.03 – 56.04 MbChr 2: 86.98 – 86.98 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein–coupled receptors (GPCR) arising from single coding-exon genes.

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000181785Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000075158Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: OR5AS1 olfactory receptor, family 5, subfamily AS, member 1".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.